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Your guide to Nitric Oxide: find out what every bodybuilder should know about Nitric Oxide
Ask any bodybuilder how creatine works, and you'll most likely hear a detailed answer describing how this nutrient helps you pack on size and add poundages to your lifts. Same thing applies for protein. But ask how Nitric Oxide works, and you may be looking at one speechless bodybuilder. And who's to blame them? The merits of Nitric Oxide supplements have only recently come to the attention of the bodybuilding community. That's why so many bodybuilders don't know how Nitric Oxide can help them jack up their strength, add slabs of rock-hard muscle to their frames, and improve their recovery time. What follows is a comprehensive guide to one of the most important molecules known to bodybuilders today. More Articles of Interest
What Is Nitric Oxide? Nitric Oxide is a compound made up of one nitrogen atom and one oxygen atom. In order for the body to create Nitric Oxide, it must do so with the help of arginine (an amino acid) and a family of enzymes called Nitric Oxide synthase (NOS). When arginine and a NOS enzyme come in contact with each other, the reaction produces Nitric Oxide along with citrulline (another amino acid). Interestingly enough, citrulline can be reversibly converted into arginine through a two-step process requiring the amino acid aspartic acid (aka aspartate). Therefore, if your aim is to amplify Nitric Oxide levels in your body, it would be in your best interest to take a supplement that provides a generous supply of all three of these amino acids. In doing so, you'll provide yourself with the precursor to Nitric Oxide (arginine), while supplying the precursors (citrulline and aspartic acid) to support and increase arginine production. Thus, your body's total arginine pool is improved. What Does Nitric Oxide Do? Nitric Oxide travels freely from cell to cell in your body directing and ordering a wide variety of functions within the body. Depending on the situation, Nitric Oxide can act as an intracellular messenger, a hormone, or a neurotransmitter. However, for the purpose of bodybuilding, we'll focus on the role of Nitric Oxide as an intracellular messenger regulating one of the body's most important processes--blood flow. How Does Nitric Oxide Work? Nitric Oxide is produced within the flat endothelial cells that line the inside of blood vessels. When the endothelial cell is stimulated--such as when the muscle contracts--it synthesizes and releases Nitric Oxide. Once released, Nitric Oxide diffuses across the endothelial cell membrane into the adjacent smooth muscle tissue of the blood vessels, causing them to relax and widen (a process called vasodilation). The result is an increase in blood flow to the stimulated area, which ultimately causes your muscles to get pumped and stay that way for around 40 minutes after training. So why do your muscles get pumped? Well, basically, the pump is one of the body's fail-safe mechanisms for preventing a decline in muscle function and performance. Blood, which is the body's primary transport medium, carries all the vital nutrients (e.g., amino acid, creatine, glucose, and oxygen) to the muscle, which are required for energy production, growth, and maintenance. Additionally, blood carries away the byproducts of metabolism (e.g., carbon dioxide and lactic acid) that fatigue the muscle and inhibit performance. Therefore, increasing blood flow to the muscle enhances growth, strength development, and recuperation. And remember, Nitric Oxide is what helps make the pump possible. However, as powerful as Nitric Oxide is, you must keep in mind that it does have its limitations, but there are ways of getting around them. The Limitations of Nitric Oxide First off, as mentioned earlier, Nitric Oxide production is limited by the available supply of arginine. However, as also mentioned earlier, supplementing with this amino acid, along with citrulline and aspartic acid, can increase arginine availability. Nevertheless, there's a caveat here, which brings us to the next issue. Nitric Oxide production is also limited by the availability of NOS enzymes. There are only so many enzymes present, so enzymes activity may be limited. Flooding your body with too much arginine and arginine precursors could be overwhelming. However, there are two ways to combat this: (1) Supplement with Pycnogenol[R] (French maritime pine bark extract) and ginsenosides (the active component in American ginseng extract), as they both stimulate and enhance the efficiency of the NOS enzymes, and (2) ensure your supplements of choice are time-released. In doing so, your body will be able to generate and sustain Nitric Oxide production longer, while making your pumps last longer too. The result? The short-term window of opportunity to benefit from the pump becomes long term. (Remember, the pump you get from training only lasts around 40 minutes.) Now, before you run out and buy individual arginine, citrulline, aspartic acid, Pycnogenol[R], and ginsenosides in an attempt to make your own Nitric Oxide-increasing homebrew, consider the following: MuscleTech researchers have recently released a supplement called PUMP-TECH[TM] that contains all of these ingredients in its patent-pending formula. On top of this, PUMP-TECH also contains tricreatine malate for additional support in muscle growth, increases in strength, and recuperation. And yes, the PUMP-TECH[TM] formula is time-released. An Educated Bodybuilder Is a Successful Bodybuilder With this information, you'll be able to effectively increase your Nitric Oxide production for incredible gains. What's more, you'll also sound like a supplement guru the next time someone asks you about Nitric Oxide. So use the information given to your advantage, and harness the true power of Nitric Oxide for yourself. Because who wouldn't want to be bigger, stronger, and able to recover faster than ever before? More Articles of Interest
Pycnogenol[R] is a registered trademark of Horphag Research Ltd. All other trademarks are owned by their trademark owners and are used with permission. COPYRIGHT 2005 Weider Publications
COPYRIGHT 2006 Gale Group
What exactly is Nitric Oxide (NO2)? Why is it such a POWERFUL bodybuilding supplement?
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Posted: Monday, November 14, 2005
What is Nitric Oxide anyway? The chemical compound nitric oxide is a gas with a chemical formula NO. It is an important signaling molecule in the body of mammals including humans, one of the few gaseous signaling molecules known. Nitric oxide (NO) is not nitrous oxide (N 2 O) or with nitrogen dioxide (NO 2 ). (Formal definition courtesy of Wikipedia)
What is L-arginine (the key ingredient used to produce Nitric Oxide) L-arginine is an amino acid found in grains and fish, meats, supplements and passes through the intestine into the blood. From the blood, it enters endothelial cells, (these are the layer of cells lining the inside of the blood and lymph vessels of the heart) where it is used to produce nitric oxide. L-arginine can be found in many foods such as meat, poultry, dairy products, and fish. The body also uses arginine to produce nitric oxide, which relaxes blood vessels. For this reason, it has been used to treat cardiovascular disorders such as heart failure, intermittent claudication, impotence, female sexual dysfunction, and interstitial cystitis. (Formal definition courtesy of Wikipedia). It can also be used as an ergogenic aid to supplement bodybuilding and sports endeavors.
L-arginine supplements cause a delayed release of Nitric Oxide into the blood. Ed Byrd (the creator of NO 2) called this the “pHyser3" effect of creating a sustained hemodilation or blood flow in the body. How does this help with bodybuilding? Nitric Oxide helps with a sustained blood pump in your body. The blood vessels that deliver muscle building agents (nutrients, creatine) to your muscles are “forced open" for an extended period of time throughout the day. This means quicker recovery, enhanced muscle gains, greater strength, more endurance due to the prolonged pump NO2 provides. You know how you feel “pumped up" after a workout? Nitric oxide helps perpetuate this muscle pump effect.
Are there other health benefits to Nitric Oxide besides bodybuilding? There is evidence that nitric oxide can prevent heart disease and stroke. The vasodilation effect nitric oxide helps protect the blood vessels from dangerous constriction. This increases the blood vessel flexibility to blood can circulate at a lower pressure. Nitric oxide may also help control platelet function, reduce artery plaque and even lower cholesterol.
Where can I get nitric oxide? Nitric oxide supplements is available at most supplement and health nutrition stores. Here are five nitric oxide products I would recommend: -Nitrix by BSN. Nitrix has quickly gained the reputation as the world's top Nitric Oxide (NO) supplements.-NO-xplode by BSN. NO-xplode uses both creatine and nitrix oxide to help you explode you bodybuilding regimen. NO-xplode is highly recommended.-A-AKG by Pro-line. This is perhaps the most economical priced nitric oxide supplement I could find.-Mid-Cycle by Fizogen. Mid Cycle effectively enhances nutrient uptake, increases cell-signaling vasodilation and promotes improved muscle torque and intercellular energy levels. Mid-Cycle is available at http://www.discountanabolics.com/p/FMC. -Cold Fusion by Legal Gear. This bodybuilding supplements is especially appropriate for serious athletes looking to maximize muscle gains with NO2. Cold fusion has twice as much NO per serving than any other nitric oxide product. Cold Fusion is available at http://www.discountanabolics.com/p/LG01. You can find nitric oxide in almost any supplement store or the internet. I have experimented (and have been ripped off a few times) with several supplement stores. I found GNC was the most accessible but way too expensive. So far the company I have been most pleased with is Rocky Mountain Sports Nutrition. They offer the best selection of bodybuilding supplements and weight loss products I could find. When it came to prices and customer service they were second to nobody. ABOUT THE AUTHOR Chad Klingensmith is an American Council on Exercise certified Personal Trainer. He has helped many clients, friends and family realize the benefits of exercise and a healthy lifestyle. Do you have any fitness questions for Chad ? Email him at fitnesschad@gmail.com .
NO Nitric Oxide Info And Products
1. What is it and where does it come from?
Nitric Oxide is a free form gas that is produced in the body and is used by the body to communicate with other cells in the body. To produce this gas, enzymes in the body break down the amino acid Arginine.Nitric Oxide is a molecule consisting of one atom of nitrogen and one atom of oxygen. The production of Nitric Oxide occurs when the amino acid L-arginine is converted into L-citruline through an enzyme group known as Nitric Oxide Synthase (NOS). The chemical process of conversion is shown in figure 1.2. What does it do and what scientific studies give evidence to support this?
Despite the claims of some in the supplement industry, there exists ample scientific literature to suggest the efficacy of Nitric Oxide products.The following was written in May 1996 in a document prepared for the Royal Society and Association of British Science Writers:
Fig. 1 - Click To Enlarge "Summary research papers continue to flood the scientific journals and insights into the biological activity and potential clinical uses of nitric oxide (NO): a gas controlling a seemingly limitless range of functions in the body. Each revelation adds to nitric oxide's already lengthy resume in controlling the circulation of the blood, regulating activities of the brain, lungs, liver, kidneys, stomach and other organs." Since the above was written in 1996, Nitric Oxide containing products have continued to be touted by those in the medical profession, as well as by athletes looking to add muscle to their frames.
The above quotation states that Nitric Oxide controls the circulation of blood, and transmits messages between nerve cells. The fact that nitric oxide increases blood flow should make it of interest to bodybuilders, as increased blood flow will serve to deliver more nutrients to muscles, thus helping muscles become larger when subject to stress.* Nitric oxide also affects the endocrine system. It affects the release of gonadotroptin releasing hormone, as well as the release of adrenaline from the adrenal medulla.* 3. Who needs it and what are some symptoms of deficiency?
Everyone REQUIRES nitric oxide to carry out key physiological processes within the body. From a bodybuilder's perspective, nitric oxide supplementation may prove useful in increasing growth due to increases in blood flow to certain areas of the body.* Signs of deficiency include physical weakness and extreme fatigue. Most "nitric oxide" supplements contain the amino acid Arginine-alpha-keto-glutarate. 4. How much should be taken? Are there any side effects?
With any amino acid containing product, overdose is a possibility. Dosing with too much arginine can lead to diarrhea, weakness and nausea. Clear dosing guidelines have not been established, so it is best to do what is known as "tolerance mapping". Take a small dosage for one week, note the benefits and the side effects, and increase the dosage until the benefits are maximized and the side effects minimized. Over time the two will converge and you will hit the optimal dose. This process is similar to "receptor mapping" for bodybuilders who use insulin.Many protein powders are fortified with amino acids, including arginine. With this in mind, pay particular attention to how much arginine you are ingesting from all supplements taken. 5. Where can I get it?
At the time of this writing, Pinnacle Brands makes NOx2. This product is very similar to the NO2 product made by MRI. IDS also make a similar product, NP2. With IDS's product, tribulus terrestris is also included. Tribulus is proven to increase testosterone levels.* The combination of tribulus and NO may prove incredibly effective. Other NO products are listed below.
Intracellular Mechanisms
When NO forms, it has a half-life of only a few seconds, in large part because superoxide anion has a high affinity for NO (both molecules have an unpaired electron making them highly reactive). Therefore, superoxide anion reduces NO bioavailability. NO also avidly binds to the heme moiety of hemoglobin (in red blood cells) and the heme moiety of the enzyme guanylyl cyclase, which is found in vascular smooth muscle cells and most other cells of the body. Therefore, when NO is formed by vascular endothelium, it rapidly diffuses into the blood where it binds to hemoglobin and subsequently broken down. It also diffuses into the vascular smooth muscle cells adjacent to the endothelium where it binds to and activates guanylyl cyclase. This enzyme catalyzes the dephosphorylation of GTP to cGMP, which serves as a second messenger for many important cellular functions, particularly for signalling smooth muscle relaxation.
Vascular Effects of NO
Vascular actions of NO include the following:
Advanced Vaso-Muscular Volumizer Promotes A Full Body Pump!The New Muscle Enhancing Phenomenon That Will Change A Generation! Nitrix has just tapped into one of the most powerful muscle building phenomenons discovered to date. This newly generated class of supplementation utilizes the breakthrough molecule NO (recently awarded The Noble Prize in 1998) to help promote new growth and visually alter your body. The Nitrix induced transformation is going to change a generation; most importantly, this ground-breaking new product is NON-HORMONAL!What To Expect From Nitrix!Week 1 - Your Body Is In A NO Loading Phase, Prepare Yourself For What Is About To Take Place! You will start to experience the initial signs of your "muscle swelling" full body pumps! You will also notice the beginning stages of an increase in your strength, recuperation and endurance.Week 2 - Nitrix Has Just Turned On The Transformation Switch! At some point in week 2 the NO switch flips on. You will really start to see and feel the power of the Nitrix induced transformation. During week 2 your strength, recuperation and endurance should noticeably increase. Your muscles will also become visibly fuller and much harder and you may also start to experience an increase in "male" size and performance.Week 3 - The Metamorphosis Has Begun And It Only Gets Better From Here! You will feel your skin tightening around your muscles and your vascularity will become exaggerated (almost freakish). You should now be experiencing rock hard, full body pumps that last all day long. Your recuperation will seem almost immediate and your strength and endurance should skyrocket. Your gains in lean mass should be unmistakable when you step on the scale and at this point everyone in the gym will be asking what you are taking.Week 4 And Beyond - Everyday You Look In The Mirror You Should Notice A New, More Muscular Physique. You should now be achieving new levels in lean mass, muscularity, and density that many people only reach after years of heavy lifting! If you think this is good, hang on; the Nitrix transformation still has a long way to go!Nitrix - The Most Advanced N.O. Supplement Ever Developed!
BSN has taken vaso-muscular volumization to the next level by developing a premier NO booster that ensures optimum NO production over current NO boosters. L-Arginine Alpha Keto-Glutarate (AAKG) has the unique ability to improve the conversion process of Arginine into NO. However, the NO boosting power of this specific amino acid is heavily dependent upon the bonded ratio of L-Arginine to AKG. After months of extensive research BSN has developed a precise bonded ratio of L-Arginine to AKG. This ratio promotes an increase in NO production over standard bonded versions of L-Arginine AKG. BSN's proprietary AAKG technology makes Nitrix the world's premier NO booster.
Recommended Use: Take 3 tablets 3 times per day (everyday). Take the first dosage in the morning on an empty stomach, the second dosage before lunch on an empty stomach, and the third dosage before dinner on an empty stomach. It is recommended to take Nitrix on an empty stomach approximately 30 minutes before each meal. Taking with food or on a full stomach, ephedra, or high amounts of glutamine will dimish its effects.
NOTES: Methocel - Controlled Release Technology!
The muscle enhancing benefits of NO are only as effective as the delivery system that is able to maintain a constant level of this molecule in the blood. Until recently NO was unable to be released at a controlled and sustained release rate. Without this required release profile the body cannot benefit from this powerful vaso-muscular volumizer. This is why BSN went to great lengths to ensure that Nitrix had the most scientifically validated and effective release protocol for NO ever developed. We enlisted the help of one of the top pharmaceutical companies in the world to develop a proven delivery system that would outperform any release profile ever developed for this new breakthrough class of supplementation.BSN's exclusive release technology (aka Methocel - a micro-polymer hydrophilic ether matrix) was developed by Dow Chemical to control the release rate of specific ingredients. Methocel provides Nitrix with a constant and steady release rate of NO and maintains its concentrations in the blood near 24 hours. BSN's controlled release technology has just opened up the unlimited muscle and performance enhancing potential of NO.The Vital Nutrient Support System!
Nitrix contains a vital support system that provides the body with specific nutrients that are required to effectively utilize the vaso-muscular volumizing properties of NO.Nutrient #1 - An Essential NO Enzyme - Nicotinamide Adenine Dinucleotide (NAD) is an essential NO enzyme that has a vital role in the conversion of L-AAKG to NO. Without the addition of this enzyme NO conversion is minimized to less than ideal levels. However, with the added support of this enzyme NO production is considerably increased to levels that may have never before been obtainable by the body.Nutrient 2 - A Key NO Donor - L-Citrulline is an amino acid that is an extremely powerful NO donor. This relatively unheard of amino acid has a significant role in the body's NO production process due to its unique ability to continually recycle itself into NO. This continuous recycling procedure promotes increased and sustained levels of NO in the blood.Nutrient 3 - A Precise Blend of Essential Phosphates - Phosphoplexx is a precise blend of essential phosphates that are crucial in the uptake and storage of nutrients in the muscle cell. Without these phosphates the body's ability to increase and store the amounts of protein (amino acids), glucose (carbohydrates), ATP, creatine, oxygen, and calcium within the muscle are significantly limited. Phosphoplexx enhances the uptake of these nutrients into the muscle which is extremely important to achieve the true potential of NO.The addition of this vital support system amplifies the body's ability to produce and significantly increase NO to optimal muscle and performance enhancing levels.
SuperPump 250Increase lean mass with your first workout! Promotes skin tearing muscle pumps, roadmap vascularity and explosive workouts! SuperPump250 in Clinical Trials: Increases lean mass in one workout! Causes rapid and measurable full muscle pumps! Rapidly increases the ratio of lean body composition. SuperPump250: Promotes intense mental focus, maximum energy and superior strength! Enhances full body vascularity! (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.) SuperPump250 - Way Beyond Nitric Oxide! The clinical trials have it! SuperPump250 has been developed through extensive research and has been shown in independent laboratory testing to promote explosive and immediate results! In one fell swoop, Gaspari Nutrition has made all other nitric oxide and creatine supplements obsolete. Thanks to a precise formulation of ingredients designed to enhance anabolic signaling and nitric delivery, SuperPump250 delivers skin-tearing pumps, road-map vascularity and incredible, explosive workouts! Once you've trained with SuperPump 250 - we dare you to train without it!
Recommended Use: As a dietary supplement, take 1-3 scoops with 4-12 oz of cold water or juice 30-40 minutes prior to training. On non-training days, take 1 scoop with 4-8 oz of cold water or juiceNo XplodeMake Every Workout A Muscle-Building Success With No-XplodeNO-Xplode is the world’s first and only pre-workout supplement that produces immediate results in energy, size, strength, pumps, performance, mental focus, and training intensity. You will literally see and feel it working within minutes of taking it! NO-Xplode has the unique ability to get you dialed in and pumped up for every single workout by inducing the strongest and most advanced nitric oxide, creatine, and body-mind stimulating surge ever developed in a supplement. No other products can say that! No other products can do that!NO Xplode Gives you Immediate Muscle And Vascular Enlargement With NO Meta-Fusion!
NO Meta-Fusion is the core of NO-Xplode. NO widens the blood vessel, which in turn accelerates blood flow to the muscle. This sudden blood surge causes mind blowing pumps and a rapid increase in the overall size and shape of your muscles. The result? NO Meta-Fusion precision delivers a powerful blend of the new muscle volumizing creatine matrix that only NO-Xplode provides.
Recommended Use: As dietary supplement, take 2-3 scoops with 8-12 oz of cold water or any beverage of your choice 30-45 minutes prior to your workout (on an empty stomach).To achieve maximum results, avoid eating a meal or drinking a protein shake within an hour of taking No-Xplode.Caution: Individuals sensitive to stimulants should begin use with half the recommended dosage (1-2 scoops) to help access your tolerance.Recommended Use on Non-Training Days: As a dietary supplement, take 1 scoop with 4-8 oz of cold water or any beverage of your choice (on an empty stomach).To avoid sleeplessness, do not take within 4 hours of bedtime. Taking No-Xplode with food or on a full stomach will diminish its effects. Additionally, while taking No-Xplode it is ideal to keep L-Glutamine powder supplementation to 10 grams or under per day. Taking a product that contains ephedrine will also diminish the effects of No-Xplode. To fully benefit from the vaso-muscular volumizing effects of No-Xplode it is recommended to take it everyday, and consume 120 oz of water per day and a diet that is rich in protein and carbohydrates. Every individual's body chemistry and weight will determine how long it takes for No-Xplode to induce its maximum effects. Many individuals may notice the initial energy, mental focus, and volumizing effects within 5-15 minutes of ingestion. These effects tend to become progressively more pronounced every few minutes thereafter. Others may begin to notice the initial signs within the 30-45 minutes of ingestion. Again, these effects tend to become progressively more pronounced every few minutes thereafter. No-Xplode induced its maximum energy and vaso-muscular volumizing effects within 1-5 hours after ingestion.
NOTES: Instant Gratification With The Muscle Volumizing Creatine Matrix
Get Dialed In, Every Single Workout, With The Ener-Tropic Xplosion!To get a maximum pump, you've got to connect with your muscles with 100% focus on every set and every rep (the mind-muscle connection). NO-Xplode's one-of-a-kind blend of methylxanthine and nootropics (brain stimulating nutrients) energizes your brain and body with the most focused intensity imaginable, within minutes of ingestion . Complete Muscle Hydration And Nutrient Saturation With Glycerol Hydrating Polymers And Phospho-Electrolyte Replacers!No Xplode's Complex Blend
This complex blend is a powerful magnet for water, protein, carbohydrates, creatine, and other muscle building nutrients within the muscle. This innovative system dramatically enhances the pump, fuels the body for intense training sessions, reduces lactic acid build up, replenishes lost electrolytes, enhances endurance and stamina, and saturates the muscle with nutrients for growth. Now You Can Start Seeing and Feeling Rapid Results For All Your Time And Effort!No More Wasting Workouts with No Xplode
Nothing is more frustrating than investing time and effort into training, and then not achieving the result you envisioned. With NO-Xplode there is no more waiting, hoping, or praying for results. No more workouts where your muscles feel and look flat, or where your mind and your muscles are not synched up. NO-Xplode begins working within minutes of taking it, it gets you dialed in and pumped for every single workout. No other products can say that. No other products can do that!A Perfect Work Out with No Xplode
Your perfect workout awaits with NO-Xplode. If you are looking for a product that has similar ingredients...you won't find it! NO-Xplode is truly revolutionary in every aspect. If you are looking for something to compare NO-Xplode to...there is nothing! If you are looking for a product that has similar ingredients...you won't find it! If you are going to wait until a knock-off comes out and try that...you will be extremely disappointed! NO-Xplode is truly revolutionary in every aspect.NO Xplode Ingredient Profile
The ingredient profile is mind-blowing ! Many of the ingredients in NO-Xplode are completely unique and relatively unheard of, and to date have never been applied to a product of this magnitude. If you think there is something out there, or that will come along, that will outperform this product - it's not possible! I spent year developing this product and it is more complicated to formulate than imaginable. Most companies are not willing to spend the time or money on trying to develop a product of this caliber. In an effort to protect NO-Xplode from knock-off companies, BSN has filed for various patents to help protect the products integrity.
،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،How Nitric Oxide Works With Bodybuilding
With bodybuilding, it seems that the latest supplement comes and goes on a regular basis. As safety and effectiveness are studied and taken into account, the latest recommendations change on a regular basis.Even substances that are considered natural may be found to be unsafe. Others that seemed to have no relation whatsoever are brought to the table as helpful, such as is the case with nitric oxide. However, even those who have adopted the benefits aren't always sure how the substance works in the body and why it seems to help build muscle mass.Many muscle builders are unsure of exactly what nitric oxide is. It is a common misconception that it is a hormone. However, that is actually not the case at all. Instead, the supplement is an amino acid, that sometimes works as a hormone in action.It carries messages between cells and this is the function that makes it work so well with bodybuilding. When the muscles work, they naturally release the substance in the body and stimulate an increase in blood flow in the area. This will make your workout routine more effective.Blood flow not only feeds the muscle, but also assists in the process of rebuilding tissue that was placed under stress. Adding a supplement of this natural chemical increases all these natural processes and brings more muscle mass to a body that is under its influence. The process that is working doesn't change, but rather it becomes prolonged and the effect is drawn out.In the body, no substance acts entirely on its own. Instead, groups of hormones, amino acids and chemicals work in synergy to achieve a common goal. With nitric oxide, these complementary chemicals are arginine, aspartic acid and citrulline. Without the appropriate balance, the desired results are not achieved.Because of this, balance is essential when supplementing for bodybuilding. It is always a good idea to take care when boosting the effectiveness of your workout. Look for a product that is time released to maintain a consistent, but effective action in the muscle cells.Whenever a regimen of strength training is taken up, a great deal of thought goes into the best tools and techniques to employ to accomplish the desired goal. Proper form is always a concern, so much so that professional trainers are often recruited to work with you.And, certainly, supplements can be a valid part of the process. However, sometimes a bit more attention to science is needed in order to gain the understanding needed to get results that are above average. Many supplements are questionable in bodybuilding. Even natural products can be used too liberally.The good news is that nitric oxide is safe and effective when proper precautions and dosage is followed. The body already makes the chemical in the natural course. However, don't make the mistake of thinking that more is always better. A balance must be maintained in order to achieve the best results.Be sure that the partner substances are present and that you don't overwhelm the body with too much of a good thing.Getting the Most From Nitric Oxide Bodybuilding
When you begin to workout with the focus on building raw muscle mass, you generally hit the gate running, full of enthusiasm and dedication. Over time, the reality of the intensity of the regimen comes into focus. This takes a great deal of daily dedication. In addition, some athletes find that they aren't getting quite the results they envisioned from their nitric oxide bodybuilding.If this situation sounds familiar to you, you may not be getting the most out of your routine, for various reasons. Bodybuilding has a sweet spot, for sure, and finding that is necessary to achieve the best and most effective results.The first thing to take a look at is your basic workout routine. There is a level of intensity that is absolutely crucial to make nitric oxide bodybuilding effective. If you do not sustain this type of a routine, you are wasting your money and your breath when it comes to using this popular bodybuilding supplement.In essence, you can only get maximum results if you are putting out the maximum effort. Nitric oxide allows for your body to push its limits. If you are not already doing so, adding a bit of extra endurance will not have the effect that is needed for an increased pump.The magic is in pushing your body a bit harder than would be possible without the supplement and this should be taken into consideration when strength training. Work to your limit, then add just a little bit more.Another consideration to look at is the dosage that you are taking into your body as a part of nitric oxide bodybuilding. The recommended amount is between 6,000-10,000 mg per day. You should resist the urge to fall prey to the idea that, surely, adding more will increase the effectiveness.That is just plain not true. In fact, you can overdose and this can decrease performance, exactly the opposite effect as desired. Taking too much nitric oxide can cause stomach cramping, weakness and even diarrhea. You could even cause your blood pressure to drop significantly, which is potentially dangerous.There is a fine balance that should be strictly adhered to, not only for safety, but also for effectiveness. You won't get more performance from more nitric oxide.There is still a lot more knowledge to be discovered when it comes to bodybuilding and the nitric oxide supplement. Initial results show a very promising relation to increased muscle mass and using the supplement. It is already present in the body's system and is easily utilized to enhance the pump.However, you should still take care that you aren't overwhelming your cells and being careless. Your body is amazing and can accomplish great things if properly cared for. Be aware of the risks and side effects and don't use the supplement until you have a basic grasp of how and why it works for bodybuilding results.Nitric oxide bodybuilding can be more effective than more standard routines. However, it must be done correctly in order to see the desired results in a safe manner.Using Nitric Oxide Products in Pill Form
When it comes using nitric oxide, the usages are considerable and many, this particular chemical has many wonderful benefits. If you feel like using this chemical would be a good idea for you in potentially improving you health, you will need to find nitric oxide products.These products will normally come in pill form and there are plenty of practical applications for these pills. Of course, before you use this or any other supplement, visit your doctor for a discussion about its benefits for you.The easiest way to find good nitric oxide products is to look on any one of the many health and fitness websites. Of particular significance are websites dedicated to weight lifting and bodybuilding. This actually makes a lot of sense considering the use of nitric oxide has become quite popular in the strength training community.For many years, strength-training types have boasted about nitric oxides ability to improve mental focus while working out. In addition, it is credited for increasing performance levels when exercising, and increasing strength training intensity as well.With many people who suffer from the malady of high blood pressure, nitric oxide products can be a huge help without having to deal with medications that can cause serious side affects. Now, that is not to say the nitric oxide does not have any side affects, however, these side affects are normally very mild ranging from diarrhea, fatigue and in some cases, nausea.If you suffer from this common condition and you are looking for an alternative to prescription medication to treat your high blood pressure, nitric oxide is a great option. However, in these situations it would be advisable to speak with your doctor about beginning or changing any regimented treatment for a condition that can be as serious as elevated blood pressure.Few conditions can have the potential to be a disastrous and as life threatening as a blood clot. This situation can cause extreme physical distress as well as having the high likelihood of being fatal. With elevated nitric oxide levels, blood flow is increased and that blood flow will not allow any blood platelets to form causing clots; clots that could potentially could break off and pose a significant risk to your health as well as your life. Increased blood flow can also help to reduce the risks of heart attacks and of strokes in many different ways.While you may feel a bit silly about purchasing anything from a bodybuilding website when the furthest thing from your mind is avid strength training, these sites are a great resource if you want to give nitric oxide products a try. Just because you are not a bodybuilder does not mean you cannot purchase items and supplements that have been designed for strength training enthusiasts.The truth is that these sorts of products are not just for bodybuilders. While it is true that these products are of great benefit to your average bodybuilder, if you are dealing with serious health conditions, or you are looking to prevent any of those conditions from ever happening, the use of nitric oxide might just be the thing.NO Nitric Oxide Might Deserve A Second Look
You may of heard the term nitric oxide (also termed as No and free gas) but you may have not given it much thought. It is not uncommon, most people would barely give it a passing thought; however, what most do not realize is just how important and beneficial this particular chemical can really be.Whether it is naturally produced in your body, or taken as a supplement, no nitric oxide is something that very well may be able to save your life.The truth is that no nitric oxide has developed a bit of a bad reputation. It actual name is nitric monoxide, which in fact is considered a key factor in air pollution. This particular gas is often what is put out by cars, cigarettes and power plant emissions. With a world that is so focused on living a green lifestyle free from harmful pollutants, one might figure that the one good part about nitric oxide is avoiding it completely.However, that sort of thinking could not be anymore wrong. This free gas is harmful in certain applications, but its beneficial applications are incredibly positive, and most of them are benefits that involve the health and fitness of the human body.Nitric oxide has many wonderful and helpful applications that far exceed the poor reputation it has gotten as an air pollutant. The key to no nitric oxide and how it helps the human body is its ability to increase and improve blood flow. This increase has multiple applications. It can help a bodybuilder or an athlete's muscle repair faster and can add muscle structure faster.This increased blood flow can lessen high blood pressure. It also can help to prevent dangerous conditions like blood clots from forming, plaque from developing in arteries and blood vessels as well as a preventative measure against heart attacks and strokes.Not only that but this chemical also has been useful in neuroscience, physiology, and immunology. If that is not enough it was also named Molecule of the Year in 1992.While the medical community has begun to understand the benefits that no nitric oxide has to offer in terms of the healing aspect, perhaps nitric oxides recent publicity has everything to do with its less serious usage, namely, its use as a supplement in the bodybuilding and fitness world. The truth is that the benefits that bodybuilder glean from nitric oxide is nothing terribly new to the inner workings of this naturally produced chemical.Bodybuilders and athletes alike are simply capitalizing on nitric oxides effects on blood flow. With increased blood flow, bodybuilders are able to rush much-needed nutrients to overloaded muscle groups. This, in turn, helps those muscles to recover faster and heal back stronger and more pronounced.It may have seemed from many people's initial thought that something like no nitric oxide would be a bad thing, and if the truth is told, there are bad sides to this particular gas. However, there are plenty of upsides to this gas as well.From helping to sculpt a body to helping to save lives and the prevention of serious health issues, all can be had from this seemingly harmful, but very beneficial chemical.
Your guide to Nitric Oxide: find out what every bodybuilder should know about Nitric Oxide
Ask any bodybuilder how creatine works, and you'll most likely hear a detailed answer describing how this nutrient helps you pack on size and add poundages to your lifts. Same thing applies for protein. But ask how Nitric Oxide works, and you may be looking at one speechless bodybuilder. And who's to blame them? The merits of Nitric Oxide supplements have only recently come to the attention of the bodybuilding community. That's why so many bodybuilders don't know how Nitric Oxide can help them jack up their strength, add slabs of rock-hard muscle to their frames, and improve their recovery time. What follows is a comprehensive guide to one of the most important molecules known to bodybuilders today. More Articles of Interest
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What Is Nitric Oxide? Nitric Oxide is a compound made up of one nitrogen atom and one oxygen atom. In order for the body to create Nitric Oxide, it must do so with the help of arginine (an amino acid) and a family of enzymes called Nitric Oxide synthase (NOS). When arginine and a NOS enzyme come in contact with each other, the reaction produces Nitric Oxide along with citrulline (another amino acid). Interestingly enough, citrulline can be reversibly converted into arginine through a two-step process requiring the amino acid aspartic acid (aka aspartate). Therefore, if your aim is to amplify Nitric Oxide levels in your body, it would be in your best interest to take a supplement that provides a generous supply of all three of these amino acids. In doing so, you'll provide yourself with the precursor to Nitric Oxide (arginine), while supplying the precursors (citrulline and aspartic acid) to support and increase arginine production. Thus, your body's total arginine pool is improved. What Does Nitric Oxide Do? Nitric Oxide travels freely from cell to cell in your body directing and ordering a wide variety of functions within the body. Depending on the situation, Nitric Oxide can act as an intracellular messenger, a hormone, or a neurotransmitter. However, for the purpose of bodybuilding, we'll focus on the role of Nitric Oxide as an intracellular messenger regulating one of the body's most important processes--blood flow. How Does Nitric Oxide Work? Nitric Oxide is produced within the flat endothelial cells that line the inside of blood vessels. When the endothelial cell is stimulated--such as when the muscle contracts--it synthesizes and releases Nitric Oxide. Once released, Nitric Oxide diffuses across the endothelial cell membrane into the adjacent smooth muscle tissue of the blood vessels, causing them to relax and widen (a process called vasodilation). The result is an increase in blood flow to the stimulated area, which ultimately causes your muscles to get pumped and stay that way for around 40 minutes after training. So why do your muscles get pumped? Well, basically, the pump is one of the body's fail-safe mechanisms for preventing a decline in muscle function and performance. Blood, which is the body's primary transport medium, carries all the vital nutrients (e.g., amino acid, creatine, glucose, and oxygen) to the muscle, which are required for energy production, growth, and maintenance. Additionally, blood carries away the byproducts of metabolism (e.g., carbon dioxide and lactic acid) that fatigue the muscle and inhibit performance. Therefore, increasing blood flow to the muscle enhances growth, strength development, and recuperation. And remember, Nitric Oxide is what helps make the pump possible. However, as powerful as Nitric Oxide is, you must keep in mind that it does have its limitations, but there are ways of getting around them. The Limitations of Nitric Oxide First off, as mentioned earlier, Nitric Oxide production is limited by the available supply of arginine. However, as also mentioned earlier, supplementing with this amino acid, along with citrulline and aspartic acid, can increase arginine availability. Nevertheless, there's a caveat here, which brings us to the next issue. Nitric Oxide production is also limited by the availability of NOS enzymes. There are only so many enzymes present, so enzymes activity may be limited. Flooding your body with too much arginine and arginine precursors could be overwhelming. However, there are two ways to combat this: (1) Supplement with Pycnogenol[R] (French maritime pine bark extract) and ginsenosides (the active component in American ginseng extract), as they both stimulate and enhance the efficiency of the NOS enzymes, and (2) ensure your supplements of choice are time-released. In doing so, your body will be able to generate and sustain Nitric Oxide production longer, while making your pumps last longer too. The result? The short-term window of opportunity to benefit from the pump becomes long term. (Remember, the pump you get from training only lasts around 40 minutes.) Now, before you run out and buy individual arginine, citrulline, aspartic acid, Pycnogenol[R], and ginsenosides in an attempt to make your own Nitric Oxide-increasing homebrew, consider the following: MuscleTech researchers have recently released a supplement called PUMP-TECH[TM] that contains all of these ingredients in its patent-pending formula. On top of this, PUMP-TECH also contains tricreatine malate for additional support in muscle growth, increases in strength, and recuperation. And yes, the PUMP-TECH[TM] formula is time-released. An Educated Bodybuilder Is a Successful Bodybuilder With this information, you'll be able to effectively increase your Nitric Oxide production for incredible gains. What's more, you'll also sound like a supplement guru the next time someone asks you about Nitric Oxide. So use the information given to your advantage, and harness the true power of Nitric Oxide for yourself. Because who wouldn't want to be bigger, stronger, and able to recover faster than ever before? More Articles of Interest
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Pycnogenol[R] is a registered trademark of Horphag Research Ltd. All other trademarks are owned by their trademark owners and are used with permission. COPYRIGHT 2005 Weider Publications
COPYRIGHT 2006 Gale Group
What exactly is Nitric Oxide (NO2)? Why is it such a POWERFUL bodybuilding supplement?
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Posted: Monday, November 14, 2005
What is Nitric Oxide anyway? The chemical compound nitric oxide is a gas with a chemical formula NO. It is an important signaling molecule in the body of mammals including humans, one of the few gaseous signaling molecules known. Nitric oxide (NO) is not nitrous oxide (N 2 O) or with nitrogen dioxide (NO 2 ). (Formal definition courtesy of Wikipedia)
What is L-arginine (the key ingredient used to produce Nitric Oxide) L-arginine is an amino acid found in grains and fish, meats, supplements and passes through the intestine into the blood. From the blood, it enters endothelial cells, (these are the layer of cells lining the inside of the blood and lymph vessels of the heart) where it is used to produce nitric oxide. L-arginine can be found in many foods such as meat, poultry, dairy products, and fish. The body also uses arginine to produce nitric oxide, which relaxes blood vessels. For this reason, it has been used to treat cardiovascular disorders such as heart failure, intermittent claudication, impotence, female sexual dysfunction, and interstitial cystitis. (Formal definition courtesy of Wikipedia). It can also be used as an ergogenic aid to supplement bodybuilding and sports endeavors.
L-arginine supplements cause a delayed release of Nitric Oxide into the blood. Ed Byrd (the creator of NO 2) called this the “pHyser3" effect of creating a sustained hemodilation or blood flow in the body. How does this help with bodybuilding? Nitric Oxide helps with a sustained blood pump in your body. The blood vessels that deliver muscle building agents (nutrients, creatine) to your muscles are “forced open" for an extended period of time throughout the day. This means quicker recovery, enhanced muscle gains, greater strength, more endurance due to the prolonged pump NO2 provides. You know how you feel “pumped up" after a workout? Nitric oxide helps perpetuate this muscle pump effect.
Are there other health benefits to Nitric Oxide besides bodybuilding? There is evidence that nitric oxide can prevent heart disease and stroke. The vasodilation effect nitric oxide helps protect the blood vessels from dangerous constriction. This increases the blood vessel flexibility to blood can circulate at a lower pressure. Nitric oxide may also help control platelet function, reduce artery plaque and even lower cholesterol.
Where can I get nitric oxide? Nitric oxide supplements is available at most supplement and health nutrition stores. Here are five nitric oxide products I would recommend: -Nitrix by BSN. Nitrix has quickly gained the reputation as the world's top Nitric Oxide (NO) supplements.-NO-xplode by BSN. NO-xplode uses both creatine and nitrix oxide to help you explode you bodybuilding regimen. NO-xplode is highly recommended.-A-AKG by Pro-line. This is perhaps the most economical priced nitric oxide supplement I could find.-Mid-Cycle by Fizogen. Mid Cycle effectively enhances nutrient uptake, increases cell-signaling vasodilation and promotes improved muscle torque and intercellular energy levels. Mid-Cycle is available at http://www.discountanabolics.com/p/FMC. -Cold Fusion by Legal Gear. This bodybuilding supplements is especially appropriate for serious athletes looking to maximize muscle gains with NO2. Cold fusion has twice as much NO per serving than any other nitric oxide product. Cold Fusion is available at http://www.discountanabolics.com/p/LG01. You can find nitric oxide in almost any supplement store or the internet. I have experimented (and have been ripped off a few times) with several supplement stores. I found GNC was the most accessible but way too expensive. So far the company I have been most pleased with is Rocky Mountain Sports Nutrition. They offer the best selection of bodybuilding supplements and weight loss products I could find. When it came to prices and customer service they were second to nobody. ABOUT THE AUTHOR Chad Klingensmith is an American Council on Exercise certified Personal Trainer. He has helped many clients, friends and family realize the benefits of exercise and a healthy lifestyle. Do you have any fitness questions for Chad ? Email him at fitnesschad@gmail.com .
NO Nitric Oxide Info And Products
1. What is it and where does it come from?
Nitric Oxide is a free form gas that is produced in the body and is used by the body to communicate with other cells in the body. To produce this gas, enzymes in the body break down the amino acid Arginine.Nitric Oxide is a molecule consisting of one atom of nitrogen and one atom of oxygen. The production of Nitric Oxide occurs when the amino acid L-arginine is converted into L-citruline through an enzyme group known as Nitric Oxide Synthase (NOS). The chemical process of conversion is shown in figure 1.2. What does it do and what scientific studies give evidence to support this?
Despite the claims of some in the supplement industry, there exists ample scientific literature to suggest the efficacy of Nitric Oxide products.The following was written in May 1996 in a document prepared for the Royal Society and Association of British Science Writers:
Fig. 1 - Click To Enlarge
<table width="190" bgcolor="#333333" border="0" cellpadding="0" cellspacing="0"><tr><td colspan="4"> </td></tr><tr><td colspan="4">[ Top 5 Sellers ]</td></tr><tr><td> </td><td valign="top">1. </td><td valign="top">Gaspari Nutrition SuperPump250</td><td> </td></tr><tr><td> </td><td valign="top">2. </td><td valign="top">BSN NO-Xplode</td><td> </td></tr><tr><td> </td><td valign="top">3. </td><td valign="top">Optimum Essential AmiN.O. Energy</td><td> </td></tr><tr><td> </td><td valign="top">4. </td><td valign="top">Nutrex HEMO-RAGE Black Ultra Concentrate</td><td> </td></tr><tr><td> </td><td valign="top">5. </td><td valign="top">Controlled Labs White Flood</td><td> </td></tr><tr><td colspan="4"> </td></tr></table> |
Everyone REQUIRES nitric oxide to carry out key physiological processes within the body. From a bodybuilder's perspective, nitric oxide supplementation may prove useful in increasing growth due to increases in blood flow to certain areas of the body.* Signs of deficiency include physical weakness and extreme fatigue. Most "nitric oxide" supplements contain the amino acid Arginine-alpha-keto-glutarate. 4. How much should be taken? Are there any side effects?
With any amino acid containing product, overdose is a possibility. Dosing with too much arginine can lead to diarrhea, weakness and nausea. Clear dosing guidelines have not been established, so it is best to do what is known as "tolerance mapping". Take a small dosage for one week, note the benefits and the side effects, and increase the dosage until the benefits are maximized and the side effects minimized. Over time the two will converge and you will hit the optimal dose. This process is similar to "receptor mapping" for bodybuilders who use insulin.Many protein powders are fortified with amino acids, including arginine. With this in mind, pay particular attention to how much arginine you are ingesting from all supplements taken. 5. Where can I get it?
At the time of this writing, Pinnacle Brands makes NOx2. This product is very similar to the NO2 product made by MRI. IDS also make a similar product, NP2. With IDS's product, tribulus terrestris is also included. Tribulus is proven to increase testosterone levels.* The combination of tribulus and NO may prove incredibly effective. Other NO products are listed below.
Intracellular Mechanisms
When NO forms, it has a half-life of only a few seconds, in large part because superoxide anion has a high affinity for NO (both molecules have an unpaired electron making them highly reactive). Therefore, superoxide anion reduces NO bioavailability. NO also avidly binds to the heme moiety of hemoglobin (in red blood cells) and the heme moiety of the enzyme guanylyl cyclase, which is found in vascular smooth muscle cells and most other cells of the body. Therefore, when NO is formed by vascular endothelium, it rapidly diffuses into the blood where it binds to hemoglobin and subsequently broken down. It also diffuses into the vascular smooth muscle cells adjacent to the endothelium where it binds to and activates guanylyl cyclase. This enzyme catalyzes the dephosphorylation of GTP to cGMP, which serves as a second messenger for many important cellular functions, particularly for signalling smooth muscle relaxation.
Vascular Effects of NO
Vascular actions of NO include the following:
- Direct vasodilation (flow dependent and receptor mediated)
- Indirect vasodilation by inhibiting vasoconstrictor influences (e.g., inhibits angiotensin II and sympathetic vasoconstriction)
- Anti-thrombotic effect - inhibits platelet adhesion to the vascular endothelium
-
Anti-inflammatory effect - inhibits leukocyte adhesion to vascular endothelium; scavenges superoxide anion - Anti-proliferative effect - inhibits smooth muscle hyperplasia
- Vasoconstriction (e.g., coronary vasospasm, elevated systemic vascular resistance, hypertension)
- Thrombosis due to platelet aggregation and adhesion to vascular endothelium
- Inflammation due to upregulation of leukocyte and endothelial adhesion molecules
- Vascular hypertrophy and stenosis
- Hypertension
- Obesity
- Dyslipidemias (particularly hypercholesterolemia and hypertriglyceridemia)
- Diabetes (both type I and II)
- Heart failure
- Atherosclerosis
- Aging
- Cigarette smoking
Advanced Vaso-Muscular Volumizer Promotes A Full Body Pump!The New Muscle Enhancing Phenomenon That Will Change A Generation! Nitrix has just tapped into one of the most powerful muscle building phenomenons discovered to date. This newly generated class of supplementation utilizes the breakthrough molecule NO (recently awarded The Noble Prize in 1998) to help promote new growth and visually alter your body. The Nitrix induced transformation is going to change a generation; most importantly, this ground-breaking new product is NON-HORMONAL!What To Expect From Nitrix!Week 1 - Your Body Is In A NO Loading Phase, Prepare Yourself For What Is About To Take Place! You will start to experience the initial signs of your "muscle swelling" full body pumps! You will also notice the beginning stages of an increase in your strength, recuperation and endurance.Week 2 - Nitrix Has Just Turned On The Transformation Switch! At some point in week 2 the NO switch flips on. You will really start to see and feel the power of the Nitrix induced transformation. During week 2 your strength, recuperation and endurance should noticeably increase. Your muscles will also become visibly fuller and much harder and you may also start to experience an increase in "male" size and performance.Week 3 - The Metamorphosis Has Begun And It Only Gets Better From Here! You will feel your skin tightening around your muscles and your vascularity will become exaggerated (almost freakish). You should now be experiencing rock hard, full body pumps that last all day long. Your recuperation will seem almost immediate and your strength and endurance should skyrocket. Your gains in lean mass should be unmistakable when you step on the scale and at this point everyone in the gym will be asking what you are taking.Week 4 And Beyond - Everyday You Look In The Mirror You Should Notice A New, More Muscular Physique. You should now be achieving new levels in lean mass, muscularity, and density that many people only reach after years of heavy lifting! If you think this is good, hang on; the Nitrix transformation still has a long way to go!Nitrix - The Most Advanced N.O. Supplement Ever Developed!
BSN has taken vaso-muscular volumization to the next level by developing a premier NO booster that ensures optimum NO production over current NO boosters. L-Arginine Alpha Keto-Glutarate (AAKG) has the unique ability to improve the conversion process of Arginine into NO. However, the NO boosting power of this specific amino acid is heavily dependent upon the bonded ratio of L-Arginine to AKG. After months of extensive research BSN has developed a precise bonded ratio of L-Arginine to AKG. This ratio promotes an increase in NO production over standard bonded versions of L-Arginine AKG. BSN's proprietary AAKG technology makes Nitrix the world's premier NO booster.
Recommended Use: Take 3 tablets 3 times per day (everyday). Take the first dosage in the morning on an empty stomach, the second dosage before lunch on an empty stomach, and the third dosage before dinner on an empty stomach. It is recommended to take Nitrix on an empty stomach approximately 30 minutes before each meal. Taking with food or on a full stomach, ephedra, or high amounts of glutamine will dimish its effects.
NOTES: Methocel - Controlled Release Technology!
The muscle enhancing benefits of NO are only as effective as the delivery system that is able to maintain a constant level of this molecule in the blood. Until recently NO was unable to be released at a controlled and sustained release rate. Without this required release profile the body cannot benefit from this powerful vaso-muscular volumizer. This is why BSN went to great lengths to ensure that Nitrix had the most scientifically validated and effective release protocol for NO ever developed. We enlisted the help of one of the top pharmaceutical companies in the world to develop a proven delivery system that would outperform any release profile ever developed for this new breakthrough class of supplementation.BSN's exclusive release technology (aka Methocel - a micro-polymer hydrophilic ether matrix) was developed by Dow Chemical to control the release rate of specific ingredients. Methocel provides Nitrix with a constant and steady release rate of NO and maintains its concentrations in the blood near 24 hours. BSN's controlled release technology has just opened up the unlimited muscle and performance enhancing potential of NO.The Vital Nutrient Support System!
Nitrix contains a vital support system that provides the body with specific nutrients that are required to effectively utilize the vaso-muscular volumizing properties of NO.Nutrient #1 - An Essential NO Enzyme - Nicotinamide Adenine Dinucleotide (NAD) is an essential NO enzyme that has a vital role in the conversion of L-AAKG to NO. Without the addition of this enzyme NO conversion is minimized to less than ideal levels. However, with the added support of this enzyme NO production is considerably increased to levels that may have never before been obtainable by the body.Nutrient 2 - A Key NO Donor - L-Citrulline is an amino acid that is an extremely powerful NO donor. This relatively unheard of amino acid has a significant role in the body's NO production process due to its unique ability to continually recycle itself into NO. This continuous recycling procedure promotes increased and sustained levels of NO in the blood.Nutrient 3 - A Precise Blend of Essential Phosphates - Phosphoplexx is a precise blend of essential phosphates that are crucial in the uptake and storage of nutrients in the muscle cell. Without these phosphates the body's ability to increase and store the amounts of protein (amino acids), glucose (carbohydrates), ATP, creatine, oxygen, and calcium within the muscle are significantly limited. Phosphoplexx enhances the uptake of these nutrients into the muscle which is extremely important to achieve the true potential of NO.The addition of this vital support system amplifies the body's ability to produce and significantly increase NO to optimal muscle and performance enhancing levels.
SuperPump 250Increase lean mass with your first workout! Promotes skin tearing muscle pumps, roadmap vascularity and explosive workouts! SuperPump250 in Clinical Trials: Increases lean mass in one workout! Causes rapid and measurable full muscle pumps! Rapidly increases the ratio of lean body composition. SuperPump250: Promotes intense mental focus, maximum energy and superior strength! Enhances full body vascularity! (These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.) SuperPump250 - Way Beyond Nitric Oxide! The clinical trials have it! SuperPump250 has been developed through extensive research and has been shown in independent laboratory testing to promote explosive and immediate results! In one fell swoop, Gaspari Nutrition has made all other nitric oxide and creatine supplements obsolete. Thanks to a precise formulation of ingredients designed to enhance anabolic signaling and nitric delivery, SuperPump250 delivers skin-tearing pumps, road-map vascularity and incredible, explosive workouts! Once you've trained with SuperPump 250 - we dare you to train without it!
Recommended Use: As a dietary supplement, take 1-3 scoops with 4-12 oz of cold water or juice 30-40 minutes prior to training. On non-training days, take 1 scoop with 4-8 oz of cold water or juiceNo XplodeMake Every Workout A Muscle-Building Success With No-XplodeNO-Xplode is the world’s first and only pre-workout supplement that produces immediate results in energy, size, strength, pumps, performance, mental focus, and training intensity. You will literally see and feel it working within minutes of taking it! NO-Xplode has the unique ability to get you dialed in and pumped up for every single workout by inducing the strongest and most advanced nitric oxide, creatine, and body-mind stimulating surge ever developed in a supplement. No other products can say that! No other products can do that!NO Xplode Gives you Immediate Muscle And Vascular Enlargement With NO Meta-Fusion!
NO Meta-Fusion is the core of NO-Xplode. NO widens the blood vessel, which in turn accelerates blood flow to the muscle. This sudden blood surge causes mind blowing pumps and a rapid increase in the overall size and shape of your muscles. The result? NO Meta-Fusion precision delivers a powerful blend of the new muscle volumizing creatine matrix that only NO-Xplode provides.
Recommended Use: As dietary supplement, take 2-3 scoops with 8-12 oz of cold water or any beverage of your choice 30-45 minutes prior to your workout (on an empty stomach).To achieve maximum results, avoid eating a meal or drinking a protein shake within an hour of taking No-Xplode.Caution: Individuals sensitive to stimulants should begin use with half the recommended dosage (1-2 scoops) to help access your tolerance.Recommended Use on Non-Training Days: As a dietary supplement, take 1 scoop with 4-8 oz of cold water or any beverage of your choice (on an empty stomach).To avoid sleeplessness, do not take within 4 hours of bedtime. Taking No-Xplode with food or on a full stomach will diminish its effects. Additionally, while taking No-Xplode it is ideal to keep L-Glutamine powder supplementation to 10 grams or under per day. Taking a product that contains ephedrine will also diminish the effects of No-Xplode. To fully benefit from the vaso-muscular volumizing effects of No-Xplode it is recommended to take it everyday, and consume 120 oz of water per day and a diet that is rich in protein and carbohydrates. Every individual's body chemistry and weight will determine how long it takes for No-Xplode to induce its maximum effects. Many individuals may notice the initial energy, mental focus, and volumizing effects within 5-15 minutes of ingestion. These effects tend to become progressively more pronounced every few minutes thereafter. Others may begin to notice the initial signs within the 30-45 minutes of ingestion. Again, these effects tend to become progressively more pronounced every few minutes thereafter. No-Xplode induced its maximum energy and vaso-muscular volumizing effects within 1-5 hours after ingestion.
NOTES: Instant Gratification With The Muscle Volumizing Creatine Matrix
- No Bloat
- No Stomach Cramps
- No Fat Gain
- Just Rock-Hard, Swollen Muscles!
Get Dialed In, Every Single Workout, With The Ener-Tropic Xplosion!To get a maximum pump, you've got to connect with your muscles with 100% focus on every set and every rep (the mind-muscle connection). NO-Xplode's one-of-a-kind blend of methylxanthine and nootropics (brain stimulating nutrients) energizes your brain and body with the most focused intensity imaginable, within minutes of ingestion . Complete Muscle Hydration And Nutrient Saturation With Glycerol Hydrating Polymers And Phospho-Electrolyte Replacers!No Xplode's Complex Blend
This complex blend is a powerful magnet for water, protein, carbohydrates, creatine, and other muscle building nutrients within the muscle. This innovative system dramatically enhances the pump, fuels the body for intense training sessions, reduces lactic acid build up, replenishes lost electrolytes, enhances endurance and stamina, and saturates the muscle with nutrients for growth. Now You Can Start Seeing and Feeling Rapid Results For All Your Time And Effort!No More Wasting Workouts with No Xplode
Nothing is more frustrating than investing time and effort into training, and then not achieving the result you envisioned. With NO-Xplode there is no more waiting, hoping, or praying for results. No more workouts where your muscles feel and look flat, or where your mind and your muscles are not synched up. NO-Xplode begins working within minutes of taking it, it gets you dialed in and pumped for every single workout. No other products can say that. No other products can do that!A Perfect Work Out with No Xplode
Your perfect workout awaits with NO-Xplode. If you are looking for a product that has similar ingredients...you won't find it! NO-Xplode is truly revolutionary in every aspect. If you are looking for something to compare NO-Xplode to...there is nothing! If you are looking for a product that has similar ingredients...you won't find it! If you are going to wait until a knock-off comes out and try that...you will be extremely disappointed! NO-Xplode is truly revolutionary in every aspect.NO Xplode Ingredient Profile
The ingredient profile is mind-blowing ! Many of the ingredients in NO-Xplode are completely unique and relatively unheard of, and to date have never been applied to a product of this magnitude. If you think there is something out there, or that will come along, that will outperform this product - it's not possible! I spent year developing this product and it is more complicated to formulate than imaginable. Most companies are not willing to spend the time or money on trying to develop a product of this caliber. In an effort to protect NO-Xplode from knock-off companies, BSN has filed for various patents to help protect the products integrity.
،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،،How Nitric Oxide Works With Bodybuilding
With bodybuilding, it seems that the latest supplement comes and goes on a regular basis. As safety and effectiveness are studied and taken into account, the latest recommendations change on a regular basis.Even substances that are considered natural may be found to be unsafe. Others that seemed to have no relation whatsoever are brought to the table as helpful, such as is the case with nitric oxide. However, even those who have adopted the benefits aren't always sure how the substance works in the body and why it seems to help build muscle mass.Many muscle builders are unsure of exactly what nitric oxide is. It is a common misconception that it is a hormone. However, that is actually not the case at all. Instead, the supplement is an amino acid, that sometimes works as a hormone in action.It carries messages between cells and this is the function that makes it work so well with bodybuilding. When the muscles work, they naturally release the substance in the body and stimulate an increase in blood flow in the area. This will make your workout routine more effective.Blood flow not only feeds the muscle, but also assists in the process of rebuilding tissue that was placed under stress. Adding a supplement of this natural chemical increases all these natural processes and brings more muscle mass to a body that is under its influence. The process that is working doesn't change, but rather it becomes prolonged and the effect is drawn out.In the body, no substance acts entirely on its own. Instead, groups of hormones, amino acids and chemicals work in synergy to achieve a common goal. With nitric oxide, these complementary chemicals are arginine, aspartic acid and citrulline. Without the appropriate balance, the desired results are not achieved.Because of this, balance is essential when supplementing for bodybuilding. It is always a good idea to take care when boosting the effectiveness of your workout. Look for a product that is time released to maintain a consistent, but effective action in the muscle cells.Whenever a regimen of strength training is taken up, a great deal of thought goes into the best tools and techniques to employ to accomplish the desired goal. Proper form is always a concern, so much so that professional trainers are often recruited to work with you.And, certainly, supplements can be a valid part of the process. However, sometimes a bit more attention to science is needed in order to gain the understanding needed to get results that are above average. Many supplements are questionable in bodybuilding. Even natural products can be used too liberally.The good news is that nitric oxide is safe and effective when proper precautions and dosage is followed. The body already makes the chemical in the natural course. However, don't make the mistake of thinking that more is always better. A balance must be maintained in order to achieve the best results.Be sure that the partner substances are present and that you don't overwhelm the body with too much of a good thing.Getting the Most From Nitric Oxide Bodybuilding
When you begin to workout with the focus on building raw muscle mass, you generally hit the gate running, full of enthusiasm and dedication. Over time, the reality of the intensity of the regimen comes into focus. This takes a great deal of daily dedication. In addition, some athletes find that they aren't getting quite the results they envisioned from their nitric oxide bodybuilding.If this situation sounds familiar to you, you may not be getting the most out of your routine, for various reasons. Bodybuilding has a sweet spot, for sure, and finding that is necessary to achieve the best and most effective results.The first thing to take a look at is your basic workout routine. There is a level of intensity that is absolutely crucial to make nitric oxide bodybuilding effective. If you do not sustain this type of a routine, you are wasting your money and your breath when it comes to using this popular bodybuilding supplement.In essence, you can only get maximum results if you are putting out the maximum effort. Nitric oxide allows for your body to push its limits. If you are not already doing so, adding a bit of extra endurance will not have the effect that is needed for an increased pump.The magic is in pushing your body a bit harder than would be possible without the supplement and this should be taken into consideration when strength training. Work to your limit, then add just a little bit more.Another consideration to look at is the dosage that you are taking into your body as a part of nitric oxide bodybuilding. The recommended amount is between 6,000-10,000 mg per day. You should resist the urge to fall prey to the idea that, surely, adding more will increase the effectiveness.That is just plain not true. In fact, you can overdose and this can decrease performance, exactly the opposite effect as desired. Taking too much nitric oxide can cause stomach cramping, weakness and even diarrhea. You could even cause your blood pressure to drop significantly, which is potentially dangerous.There is a fine balance that should be strictly adhered to, not only for safety, but also for effectiveness. You won't get more performance from more nitric oxide.There is still a lot more knowledge to be discovered when it comes to bodybuilding and the nitric oxide supplement. Initial results show a very promising relation to increased muscle mass and using the supplement. It is already present in the body's system and is easily utilized to enhance the pump.However, you should still take care that you aren't overwhelming your cells and being careless. Your body is amazing and can accomplish great things if properly cared for. Be aware of the risks and side effects and don't use the supplement until you have a basic grasp of how and why it works for bodybuilding results.Nitric oxide bodybuilding can be more effective than more standard routines. However, it must be done correctly in order to see the desired results in a safe manner.Using Nitric Oxide Products in Pill Form
When it comes using nitric oxide, the usages are considerable and many, this particular chemical has many wonderful benefits. If you feel like using this chemical would be a good idea for you in potentially improving you health, you will need to find nitric oxide products.These products will normally come in pill form and there are plenty of practical applications for these pills. Of course, before you use this or any other supplement, visit your doctor for a discussion about its benefits for you.The easiest way to find good nitric oxide products is to look on any one of the many health and fitness websites. Of particular significance are websites dedicated to weight lifting and bodybuilding. This actually makes a lot of sense considering the use of nitric oxide has become quite popular in the strength training community.For many years, strength-training types have boasted about nitric oxides ability to improve mental focus while working out. In addition, it is credited for increasing performance levels when exercising, and increasing strength training intensity as well.With many people who suffer from the malady of high blood pressure, nitric oxide products can be a huge help without having to deal with medications that can cause serious side affects. Now, that is not to say the nitric oxide does not have any side affects, however, these side affects are normally very mild ranging from diarrhea, fatigue and in some cases, nausea.If you suffer from this common condition and you are looking for an alternative to prescription medication to treat your high blood pressure, nitric oxide is a great option. However, in these situations it would be advisable to speak with your doctor about beginning or changing any regimented treatment for a condition that can be as serious as elevated blood pressure.Few conditions can have the potential to be a disastrous and as life threatening as a blood clot. This situation can cause extreme physical distress as well as having the high likelihood of being fatal. With elevated nitric oxide levels, blood flow is increased and that blood flow will not allow any blood platelets to form causing clots; clots that could potentially could break off and pose a significant risk to your health as well as your life. Increased blood flow can also help to reduce the risks of heart attacks and of strokes in many different ways.While you may feel a bit silly about purchasing anything from a bodybuilding website when the furthest thing from your mind is avid strength training, these sites are a great resource if you want to give nitric oxide products a try. Just because you are not a bodybuilder does not mean you cannot purchase items and supplements that have been designed for strength training enthusiasts.The truth is that these sorts of products are not just for bodybuilders. While it is true that these products are of great benefit to your average bodybuilder, if you are dealing with serious health conditions, or you are looking to prevent any of those conditions from ever happening, the use of nitric oxide might just be the thing.NO Nitric Oxide Might Deserve A Second Look
You may of heard the term nitric oxide (also termed as No and free gas) but you may have not given it much thought. It is not uncommon, most people would barely give it a passing thought; however, what most do not realize is just how important and beneficial this particular chemical can really be.Whether it is naturally produced in your body, or taken as a supplement, no nitric oxide is something that very well may be able to save your life.The truth is that no nitric oxide has developed a bit of a bad reputation. It actual name is nitric monoxide, which in fact is considered a key factor in air pollution. This particular gas is often what is put out by cars, cigarettes and power plant emissions. With a world that is so focused on living a green lifestyle free from harmful pollutants, one might figure that the one good part about nitric oxide is avoiding it completely.However, that sort of thinking could not be anymore wrong. This free gas is harmful in certain applications, but its beneficial applications are incredibly positive, and most of them are benefits that involve the health and fitness of the human body.Nitric oxide has many wonderful and helpful applications that far exceed the poor reputation it has gotten as an air pollutant. The key to no nitric oxide and how it helps the human body is its ability to increase and improve blood flow. This increase has multiple applications. It can help a bodybuilder or an athlete's muscle repair faster and can add muscle structure faster.This increased blood flow can lessen high blood pressure. It also can help to prevent dangerous conditions like blood clots from forming, plaque from developing in arteries and blood vessels as well as a preventative measure against heart attacks and strokes.Not only that but this chemical also has been useful in neuroscience, physiology, and immunology. If that is not enough it was also named Molecule of the Year in 1992.While the medical community has begun to understand the benefits that no nitric oxide has to offer in terms of the healing aspect, perhaps nitric oxides recent publicity has everything to do with its less serious usage, namely, its use as a supplement in the bodybuilding and fitness world. The truth is that the benefits that bodybuilder glean from nitric oxide is nothing terribly new to the inner workings of this naturally produced chemical.Bodybuilders and athletes alike are simply capitalizing on nitric oxides effects on blood flow. With increased blood flow, bodybuilders are able to rush much-needed nutrients to overloaded muscle groups. This, in turn, helps those muscles to recover faster and heal back stronger and more pronounced.It may have seemed from many people's initial thought that something like no nitric oxide would be a bad thing, and if the truth is told, there are bad sides to this particular gas. However, there are plenty of upsides to this gas as well.From helping to sculpt a body to helping to save lives and the prevention of serious health issues, all can be had from this seemingly harmful, but very beneficial chemical.